Delayed Radiation Injuries (Soft Tissue and Bony Necrosis) and Potential for Future Research | Canada Hyperbarics
Review Undersea Hyperb Med 2026

Delayed Radiation Injuries (Soft Tissue and Bony Necrosis) and Potential for Future Research

Feldmeier J, Gesell L — Undersea Hyperb Med, 2026

Tier 2 — Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This review chapter explored the application of hyperbaric oxygen therapy (HBOT) for treating and preventing late radiation injuries, examining its safety for cancer patients and identifying potential areas for future research.

What They Found

Billing records from the United States indicate that delayed radiation injuries are the most frequent reason for hyperbaric treatments, making up approximately 40% of all billings. The review emphasizes that HBOT is beneficial as part of a multi-disciplinary approach, particularly when bone is involved and in conjunction with surgical interventions such as tissue flaps and skin grafts.

What This Means for Canadian Patients

For Canadian patients suffering from delayed radiation injuries, including those affecting soft tissue and bone, this review reinforces that HBOT can be a valuable part of a comprehensive treatment strategy. It suggests that combining HBOT with other therapies, such as surgery, may offer the best chance for successful recovery from these complex injuries.

Canadian Relevance

This study covers delayed radiation injury and osteoradionecrosis, which are Health Canada-recognized indications for hyperbaric oxygen therapy.

Study Limitations

As a review, this study synthesizes existing literature, meaning its conclusions are dependent on the quality and scope of the studies it analyzed rather than generating new clinical data.

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Study Details

Study Type Review
Category Radiation Injury
Source Pubmed
PubMed ID 41979533
Year Published 2026
Journal Undersea Hyperb Med
MeSH Terms Humans; Hyperbaric Oxygenation; Radiation Injuries; Osteoradionecrosis; Soft Tissue Injuries; Osteonecrosis; Time Factors; Biomedical Research

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.