[A new transportable machine for the preservation of livers to be transplanted by means of hyperbaric oxygenation perfusion] | Canada Hyperbarics Skip to main content
Study Chir Ital 2007

[A new transportable machine for the preservation of livers to be transplanted by means of hyperbaric oxygenation perfusion]

Rubbini M, Longobardi P, Rimessi A, Pinton P, Morri A, Semprini G, et al. — Chir Ital, 2007

View Original on PubMed PMID 18019646
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers developed a portable machine to continuously perfuse pig livers with hyperbaric oxygen at cool temperatures for up to 24 hours to improve organ preservation for transplantation.

What They Found

Livers perfused for up to 15 hours showed a mitochondrial activity (FAU) of 169.40 +/- 5.5, compared to 100 for control livers. Livers perfused for up to 24 hours had an FAU value of 139.18 +/- 10.7, also higher than the control value of 100, indicating cell viability.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study was conducted on pig livers, and its findings may not directly apply to human organ preservation.

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Study Details

Study Type Study
Category Uncategorised
Source Pubmed
PubMed ID 18019646
Year Published 2007
Journal Chir Ital
MeSH Terms Adenosine; Allopurinol; Animals; Cell Survival; Equipment Design; Glutathione; Humans; Hyperbaric Oxygenation; Insulin; Liver; Liver Function Tests; Liver Transplantation; Mitochondria, Liver; Organ Preservation; Organ Preservation Solutions; Raffinose; Swine; Temperature; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.