Adjunctive Hyperbaric Oxygen Therapy or Intratympanic Steroids in Sudden Sensorineural Hearing Loss? | Canada Hyperbarics Skip to main content
Retrospective Study The Laryngoscope 2025 Canadian

Adjunctive Hyperbaric Oxygen Therapy or Intratympanic Steroids in Sudden Sensorineural Hearing Loss?

Spiegel JL, De Biasio MJ, Sampieri G, Ungar OJ, Bajin MD, Lin VYW, et al. — The Laryngoscope, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a retrospective study to compare the additive effect of hyperbaric oxygen therapy (HBOT) to intratympanic steroid injections (ITSI) for sudden sensorineural hearing loss (SSNHL).

What They Found

Among 119 patients (73 ITSI, 46 HBOT+ITSI), both groups showed significant pre-to-posttreatment improvement in hearing outcomes (p < 0.001). However, there was no significant difference in improvement between the HBOT+ITSI and ITSI-only groups for pure tone average (p=0.49), speech recognition threshold (p=0.07), or word recognition score (p=0.55). Notably, 25.8% of HBOT responders showed no initial response to ITSI alone but improved after an average of 17.5 HBOT dives.

What This Means for Canadian Patients

Canadian patients with sudden sensorineural hearing loss might not benefit from adjunctive hyperbaric oxygen therapy concurrently with intratympanic steroids. However, for those who do not respond to initial steroid treatment, HBOT could be considered as a subsequent option.

Canadian Relevance

This study includes a Canadian author, indicating potential contributions from Canadian researchers to the understanding and treatment of sudden sensorineural hearing loss. The findings are relevant to treatment protocols for SSNHL in Canada.

Study Limitations

As a retrospective study, this research is limited by its design, which may introduce biases and confounders.

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Study Details

Study Type Retrospective Study
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 41431852
Year Published 2025
Journal The Laryngoscope

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.