Alternobaric oxygen therapy in long-term treatment... (2002 study) Skip to main content
Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2002

Alternobaric oxygen therapy in long-term treatment of Ménière's disease.

Fattori B, De Iaco G, Nacci A, Casani A, Ursino F, Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2002

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Doctors compared a hyperbaric oxygen treatment called alternobaric oxygen therapy with standard medication in patients with Meniere's disease, a condition that causes vertigo and hearing problems.

What They Found

A controlled clinical study of 20 patients treated with alternobaric oxygen therapy (ABOT) versus 18 patients treated with glycerol and betahistine found no statistically significant difference between the two groups after the first 15 days of treatment, with both groups followed for up to four years. Over the longer four-year follow-up, the abstract reports that ABOT-treated patients had significantly fewer episodes of vertigo and improved outcomes compared to the control group, though the abstract does not give the specific numbers for this later comparison. Hearing thresholds and tinnitus frequency were also tracked in both groups using standard hearing and equilibrium criteria.

What This Means for Canadian Patients

For people with Meniere's disease, this study suggests alternobaric oxygen therapy may reduce vertigo episodes over several years of treatment, though it showed no clear early advantage over standard medication in the first 15 days. The treatment protocol involved repeated sessions over multiple years, which is a significant time commitment patients should discuss with their doctor.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The abstract does not report specific numerical results for its four-year follow-up comparison, and with only 20 and 18 patients in the two groups, the small sample size limits how confidently these findings can be generalized.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 12797667
Year Published 2002
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Adult; Age of Onset; Endolymph; Female; Follow-Up Studies; Hearing Loss, Sensorineural; Humans; Hyperbaric Oxygenation; Male; Meniere Disease; Middle Aged; Regression Analysis; Tinnitus; Vertigo

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This study relates to Sudden Sensorineural Hearing Loss. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology