What Researchers Did
Researchers investigated the combined use of autologous bone marrow-mononuclear cell transplantation and hyperbaric oxygen therapy in 7 patients with ischemic limbs due to peripheral arterial disease.
What They Found
All 7 patients experienced some improvement in their symptoms, and transcutaneous oxygen partial pressure increased in 5 patients. No side effects were observed, suggesting the combined therapy may be safe and effective for therapeutic angiogenesis.
Canadian Relevance
This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or patients.
Study Limitations
A significant limitation of this study is the very small sample size of only 7 patients, which limits the generalizability of the findings.