Changes in gas metabolism and tissue oxygen balance during the hyperbaric oxygenation of patients with chronic thrombotic obliterating diseases of the extremities.

What Researchers Did

Researchers investigated gas exchange and tissue oxygen balance in 44 patients with chronic thromboobliterating disease of the extremities before and after hyperbaric oxygenation therapy.

What They Found

In 44 patients, hyperbaric oxygenation (1.7-2.0 ata for 40-60 minutes) led to the normalization of metabolic processes in ischaemic tissue. This therapy also eliminated oxygen deficit and corrected deviations in acid-base status.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in 1978 and published in a Russian journal.

Study Limitations

Limitations include the small sample size of 44 patients, the lack of a control group, and the study's age, which may not reflect current medical practices.