Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2020

Clinical efficacy of adjuvant therapy with hyperbaric oxygen in diabetic nephropathy.

Cardenas Ureña KG, Ramírez Nava JC, Márquez Celedonio FG, Salas Nolasco OI, Villegas Domínguez JE, Crespo-Cortés CN — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2020

View Original on PubMed PMID 32931667

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted an experimental study to evaluate the efficacy of adjuvant hyperbaric oxygen therapy in patients with stage 3 and 4 diabetic kidney disease.

What They Found

The hyperbaric oxygen (HBO2) group showed a decrease in urinary albumin/creatinine ratio (UACR) from 1452.9 mg/g to 876.1 mg/g (p=0.06), while the control group's UACR remained stable. Additionally, the estimated glomerular filtration rate (eGFR) in the HBO2 group increased from 27.3 mL/min/1.73m2 to 34.4 mL/min/1.73m2 (p=0.017), whereas the control group's eGFR decreased from 30.1 mL/min/1.73m2 to 22.2 mL/min/1.73m2 (p=0.004).

Canadian Relevance

This study was not conducted in Canada and does not have direct Canadian relevance.

Study Limitations

The study's generalizability may be limited by its specific patient population and experimental design.

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Study Details

Study Type	Clinical Study
Category	Uncategorised
Source	Pubmed
PubMed ID	32931667
Year Published	2020
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Adult; Aged; Albumins; Case-Control Studies; Creatinine; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Hyperbaric Oxygenation; Hypertension; Male; Middle Aged; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.