[Comparative study of the effect of drug therapy and its combination with hyperbaric oxygenation and hemosorption on stable angina pectoris] | Canada Hyperbarics Skip to main content
RCT Kardiologiia 1991

[Comparative study of the effect of drug therapy and its combination with hyperbaric oxygenation and hemosorption on stable angina pectoris]

Markarian S, Shirinskaia G, Starostin S, Zagvozkin V — Kardiologiia, 1991

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers studied 77 men under 60 years old with stable angina, comparing drug therapy alone to drug therapy combined with either hyperbaric oxygenation (HBOT) or hemosorption.

What They Found

All three patient groups experienced a reduction in the frequency of resting and exercise anginal attacks. However, only the group receiving drug therapy combined with hemosorption showed increased exercise tolerance and a significant fall in total and high-density lipoprotein cholesterol levels. The study concluded that hyperbaric oxygenation and hemosorption did not significantly improve the degree of stable angina beyond the effects of drug therapy.

What This Means for Canadian Patients

This study suggests that HBOT may not be an effective add-on treatment for stable angina in Canadian patients. Individuals with stable angina should continue to follow standard drug therapy as prescribed by their healthcare providers.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study was conducted in 1991, and the abstract does not specify the hyperbaric oxygenation protocols used, which may limit the applicability of its findings to current practices.

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Study Details

Study Type RCT
Category Uncategorised
Source Pubmed
PubMed ID 1753612
Year Published 1991
Journal Kardiologiia
MeSH Terms Adult; Angina Pectoris; Combined Modality Therapy; Hemoperfusion; Humans; Hyperbaric Oxygenation; Male; Middle Aged

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.