Comparison of two different steroid treatments with hyperbaric oxygen for idiopathic sudden sensorineural hearing loss | Canada Hyperbarics Skip to main content
RCT Eur Arch Otorhinolaryngol 2016

Comparison of two different steroid treatments with hyperbaric oxygen for idiopathic sudden sensorineural hearing loss

Sevil E, Bercin S, Muderris T, Gul F, Kiris M — Eur Arch Otorhinolaryngol, 2016

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a prospective trial to compare the efficacy of intratympanic steroid plus hyperbaric oxygen therapy versus intravenous steroid plus hyperbaric oxygen therapy for idiopathic sudden sensorineural hearing loss.

What They Found

For mild-to-moderate idiopathic sudden sensorineural hearing loss, intratympanic steroid plus hyperbaric oxygen (HBO) therapy resulted in a mean hearing gain of 19 dB and a 78.9% successful treatment rate, compared to 18 dB gain and 70.5% success with intravenous steroid plus HBO. In severe cases, the intratympanic plus HBO group achieved a mean hearing gain of 33 dB and an 81.8% success rate, while the intravenous plus HBO group showed 33.5 dB gain and 58.2% success.

What This Means for Canadian Patients

The study suggests that intratympanic steroid combined with hyperbaric oxygen may offer slightly better success rates, especially for severe hearing loss, compared to intravenous steroids with hyperbaric oxygen. Patients experiencing sudden hearing loss could discuss these treatment options with their audiologists or ENT specialists.

Canadian Relevance

This study was not conducted in Canada and has no direct Canadian connection.

Study Limitations

A limitation of this study is the relatively small sample size within each subgroup, which may affect the generalizability of the findings.

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Study Details

Study Type RCT
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 26538427
Year Published 2016
Journal Eur Arch Otorhinolaryngol
MeSH Terms Adult; Audiometry, Pure-Tone; Combined Modality Therapy; Dexamethasone; Dose-Response Relationship, Drug; Drug Administration Routes; Ear, Middle; Female; Glucocorticoids; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Male; Methylprednisolone; Middle Aged; Severity of Illness Index; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.