Comparison of Two Different Treatment Protocols Using Systemic and Intratympanic Steroids with and without Hyperbaric Oxygen Therapy in Patients with Severe to Profound Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial. | Canada Hyperbarics Skip to main content
RCT Audiology & neuro-otology 2018

Comparison of Two Different Treatment Protocols Using Systemic and Intratympanic Steroids with and without Hyperbaric Oxygen Therapy in Patients with Severe to Profound Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial.

Cho I, Lee HM, Choi SW, Kong SK, Lee IW, Goh EK, et al. — Audiology & neuro-otology, 2018

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomized controlled trial comparing oral and intratympanic steroids with or without hyperbaric oxygen therapy (HBOT) in 60 patients with severe to profound idiopathic sudden sensorineural hearing loss (ISSNHL).

What They Found

The group receiving HBOT in addition to steroids showed significantly better hearing levels at 500 Hz (p < 0.05) after 1 month and at 1 kHz (p < 0.05) after 3 months. Word discrimination scores also improved significantly more in the HBOT group after 3 months, with per-protocol analysis showing 66.4 ± 13.3 for the HBOT group.

What This Means for Canadian Patients

For Canadian patients with severe to profound ISSNHL, adding hyperbaric oxygen therapy to standard steroid treatment may offer improved hearing outcomes. This could be a valuable option, especially given the typically poor prognosis for this condition.

Canadian Relevance

This study was not conducted in Canada and therefore has no direct Canadian relevance.

Study Limitations

The relatively small sample size of 60 patients limits the generalizability of these findings.

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Study Details

Study Type RCT
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 30380530
Year Published 2018
Journal Audiology & neuro-otology
MeSH Terms Administration, Oral; Adult; Aged; Audiometry, Pure-Tone; Clinical Protocols; Combined Modality Therapy; Female; Glucocorticoids; Hearing; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Injection, Intratympanic; Male

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.