Could hyperbaric oxygen be an effective therapy option for pathological scars? A systematic review and meta-analysis | Canada Hyperbarics Skip to main content
Meta-Analysis J Plast Surg Hand Surg 2023

Could hyperbaric oxygen be an effective therapy option for pathological scars? A systematic review and meta-analysis

Xie R, Zhong A, Wu J, Cen Y, Chen J — J Plast Surg Hand Surg, 2023

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis to evaluate the efficacy of hyperbaric oxygen (HBO) therapy for pathological scars.

What They Found

Hyperbaric oxygen (HBO) therapy significantly reduced the recurrence rate of pathological scars after surgery and radiotherapy (OR = 0.26, 95% CI: 0.13-0.52, p = 0.0001). Patients receiving HBO also reported higher satisfaction (OR = 4.45, 95% CI: 1.49-13.30, p = 0.007) and showed significant improvement in Vancouver Scar Scale scores (SMD: -3.82, 95% CI: -6.07 to -0.49, p = 0.02).

What This Means for Canadian Patients

For Canadian patients with pathological scars, hyperbaric oxygen therapy may offer a new treatment option to reduce recurrence and improve scar appearance and patient satisfaction. This could potentially lead to better long-term outcomes and quality of life for those affected by severe scarring.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The meta-analysis was limited by the small number of included studies (four) and their heterogeneous designs, including only one randomized controlled trial.

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Study Details

Study Type Meta-Analysis
Category Systematic Reviews
Source Pubmed
PubMed ID 35584798
Year Published 2023
Journal J Plast Surg Hand Surg
MeSH Terms Humans; Cicatrix; Hyperbaric Oxygenation; Patient Satisfaction; Oxygen; Treatment Outcome; Randomized Controlled Trials as Topic

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.