Clinical Study Diving and hyperbaric medicine 2024

Effect of hyperbaric oxygen treatment on ischaemia-reperfusion injury in rats detorsioned after experimental ovarian torsion.

Bulutlar E, Yilmaz A, Uluutku Bulutlar GB, Aslan Y, Bozdağ HN, Küçükodaci Z — Diving and hyperbaric medicine, 2024

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effect of hyperbaric oxygen treatment (HBOT) on ischaemia-reperfusion injury in rats with experimental ovarian torsion-detorsion.

What They Found

In 27 rats, hyperbaric oxygen treatment (HBOT) significantly reduced markers of oxidative stress, such as 8-hydroxy-2'-deoxyguanosine and malondialdehyde, and decreased oedema, vascular occlusion, neutrophilic infiltration, and follicular cell damage. Additionally, anti-Mullerian hormone levels were higher in the HBOT group compared to the torsion-detorsion group.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation is that this study was conducted in rats, meaning the findings may not directly translate to human patients.

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Study Details

Study Type	Clinical Study
Category	Uncategorised
Source	Pubmed
PubMed ID	38507906
Year Published	2024
Journal	Diving and hyperbaric medicine
MeSH Terms	Humans; Female; Rats; Animals; Ovarian Torsion; Rats, Wistar; Antioxidants; Hyperbaric Oxygenation; Oxygen; Reperfusion Injury

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.