Effectiveness of hyperbaric oxygen therapy for virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. | Canada Hyperbarics Skip to main content
Clinical Study International journal of hematology 2021

Effectiveness of hyperbaric oxygen therapy for virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation.

Hosokawa K, Aoki G, Ohata K, Takamatsu H, Nakagawa N, Imi T, et al. — International journal of hematology, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared hyperbaric oxygen therapy with conventional treatment for virus-associated hemorrhagic cystitis in 16 patients after allogeneic hematopoietic stem cell transplantation.

What They Found

All 8 patients receiving hyperbaric oxygen therapy achieved complete remission within a median of 14.5 days, compared to 5 out of 8 (62.5%) patients receiving conventional therapy. Furthermore, transplant-related mortality at day 100 was significantly lower in the hyperbaric oxygen group (0%) compared to the conventional therapy group (14.2%, P < 0.05).

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The small sample size of only 16 patients limits the generalizability of these findings.

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Study Details

Study Type Clinical Study
Category Uncategorised
Source Pubmed
PubMed ID 33728556
Year Published 2021
Journal International journal of hematology
MeSH Terms Adenoviridae; Adenoviridae Infections; Adult; BK Virus; Cystitis; Female; Hematopoietic Stem Cell Transplantation; Hemorrhage; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Polyomavirus Infections; Transplantation, Homologous; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.