Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2022

Effects of hyperbaric oxygen treatment on liver and kidney tissue in chronic arsenic toxicity.

Eroğlu HA, Büyük B, Öztopuz Ö, Makav M, Aydeğer C — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2022

View Original on PubMed PMID 36446292

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Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effectiveness of hyperbaric oxygen (HBO2) therapy on liver and kidney tissues in rats with chronic arsenic toxicity.

What They Found

In 24 male Wistar albino rats, chronic arsenic exposure (5 mg/kg/day for 60 days) caused significant damage to liver and kidney tissues. Hyperbaric oxygen therapy (2 ATA for 90 minutes daily for five days) reduced inflammatory cell infiltration, sinusoidal congestion, and hydropic degeneration in liver tissue. Similar protective effects were observed in kidney tissue, with the arsenic-plus-HBO2 group showing less damage than the arsenic-only group.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is that it was conducted on rats, meaning the findings may not directly translate to human patients.

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Study Details

Study Type	Clinical Study
Category	Uncategorised
Source	Pubmed
PubMed ID	36446292
Year Published	2022
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Rats; Animals; Humans; Male; Infant; Hyperbaric Oxygenation; Oxygen; Arsenic; Drinking Water; Liver; Graft vs Host Disease; Kidney; Rats, Wistar

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.