Efficacy of hyperbaric oxygen combined with dual antiplatelet therapy in elderly patients with acute cerebral infarction and its impact on nerve factors

What Researchers Did

Researchers compared standard dual antiplatelet therapy (DAPT) with DAPT plus hyperbaric oxygen therapy (HBOT) in 122 elderly patients with acute cerebral infarction, administering HBOT for 3 consecutive daily sessions.

What They Found

The group receiving HBOT combined with DAPT showed a higher total effective rate and improved daily living activities (higher Barthel Index scores) compared to the DAPT-only group. They also exhibited better neurological scores (lower NIHSS and CSS), reduced inflammation (lower MMP-9, IL-6, CRP), and improved blood flow.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study involved a relatively small number of patients and a short treatment duration of only three daily sessions.