Efficacy of hyperbaric oxygen salvage therapy for sudden sensorineural hearing loss after ineffective primary treatment in the Slovak Republic | Canada Hyperbarics Skip to main content
Study Undersea Hyperb Med 2025

Efficacy of hyperbaric oxygen salvage therapy for sudden sensorineural hearing loss after ineffective primary treatment in the Slovak Republic

Krajčovičová Z, Zigo R, Meluš V, Králová E — Undersea Hyperb Med, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers in Slovakia evaluated HBOT as salvage therapy for 70 patients with sudden sensorineural hearing loss who had not responded to primary corticosteroid treatment within 1 to 3 months of onset.

What They Found

Patients with severe hearing loss greater than 60 dB showed statistically significant improvements, with mean gains of 14.5 dB in low, 11.2 dB in mid, and 13.2 dB in high frequencies. Over 54% of severely affected patients gained 5 dB or more. Patients with mild-to-moderate loss did not show significant benefit.

What This Means for Canadian Patients

HBOT may still benefit Canadian patients with severe sudden hearing loss even weeks after onset and after steroids have failed, suggesting a role for late salvage treatment that could prevent permanent profound deafness.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

Lack of a sham control group and heterogeneity in prior treatment regimens limit conclusions about whether HBOT independently drove the observed improvements.

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Study Details

Study Type Study
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 40819352
Year Published 2025
Journal Undersea Hyperb Med
MeSH Terms Humans; Hyperbaric Oxygenation; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Male; Female; Salvage Therapy; Middle Aged; Adult; Aged; Treatment Outcome; Slovakia; Auditory Threshold; Severity of Illness Index; Young Adult; Treatment Failure

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.