Efficacy of the Additional Effect of Stellate Ganglion Block in Combination of Intratympanic Steroid and Hyperbaric Oxygen Therapy for Refractory Sudden Sensorineural Hearing Loss | Canada Hyperbarics Skip to main content
Study J Int Adv Otol 2026

Efficacy of the Additional Effect of Stellate Ganglion Block in Combination of Intratympanic Steroid and Hyperbaric Oxygen Therapy for Refractory Sudden Sensorineural Hearing Loss

Li H, Zhao C, Zhang W, Fu Y — J Int Adv Otol, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a retrospective study to investigate if adding stellate ganglion block (SGB) to hyperbaric oxygen therapy (HBO) and intratympanic steroids (ITS) improved outcomes for patients with refractory sudden sensorineural hearing loss (RSSNHL).

What They Found

Both treatment groups showed post-treatment hearing improvement (P < .05), but the group receiving SGB in addition to HBO and ITS achieved greater hearing gain, higher efficacy rates, and superior low-frequency recovery (P < .05). This triple therapy group also experienced significantly better tinnitus relief and psychological outcomes (P < .05). Earlier therapy initiation and lower baseline hearing thresholds were associated with greater hearing improvement.

What This Means for Canadian Patients

For Canadian patients with refractory sudden sensorineural hearing loss, this study suggests that combining hyperbaric oxygen therapy and intratympanic steroids with a stellate ganglion block could offer a more effective salvage treatment. This approach may lead to better hearing recovery, particularly in low-frequency ranges, and also help reduce tinnitus and improve psychological well-being. Early intervention appears to be key for better results.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a retrospective study, meaning it looked back at existing patient data, which can limit the control over variables and introduce potential biases.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Study
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 42345410
Year Published 2026
Journal J Int Adv Otol
MeSH Terms Humans; Hyperbaric Oxygenation; Female; Retrospective Studies; Male; Hearing Loss, Sudden; Salvage Therapy; Treatment Outcome; Hearing Loss, Sensorineural; Stellate Ganglion; Middle Aged; Combined Modality Therapy; Injection, Intratympanic; Adult; Audiometry, Pure-Tone; Autonomic Nerve Block; Glucocorticoids

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This study relates to Sudden Sensorineural Hearing Loss. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: June 26, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology