Evaluating hyperbaric oxygen therapy as an adjunct to corticosteroids in sudden sensorineural hearing loss: a systematic review and meta-analysis. | Canada Hyperbarics Skip to main content
Meta-Analysis European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - 2025

Evaluating hyperbaric oxygen therapy as an adjunct to corticosteroids in sudden sensorineural hearing loss: a systematic review and meta-analysis.

Moghib K, Dawoud ALA, Altalab G, Syed MS, Salomon I, Musse HAY, et al. — European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - , 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis of 14 randomized controlled trials involving 794 participants to evaluate hyperbaric oxygen therapy (HBOT) combined with systemic corticosteroids for sudden sensorineural hearing loss (SSNHL).

What They Found

The combined therapy of hyperbaric oxygen therapy and systemic corticosteroids significantly improved low-frequency hearing thresholds (SMD: 0.83, 95% CI: 0.66-1.00, p < 0.0001). This combination also increased the odds of complete hearing recovery by more than twofold (OR: 2.05, 95% CI: 1.41-2.98, p = 0.0002).

What This Means for Canadian Patients

Canadian patients experiencing sudden sensorineural hearing loss may benefit from hyperbaric oxygen therapy as an adjunct to standard corticosteroid treatment. This combined approach could lead to better hearing recovery and improved quality of life compared to corticosteroids alone.

Canadian Relevance

This study did not include any Canadian participants or researchers, and no Canadian data were analyzed.

Study Limitations

The abstract indicates that significant limitations were present, which could include heterogeneity among the included studies or potential publication bias.

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Study Details

Study Type Meta-Analysis
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 40405024
Year Published 2025
Journal European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology -
MeSH Terms Humans; Hyperbaric Oxygenation; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Combined Modality Therapy; Adrenal Cortex Hormones; Randomized Controlled Trials as Topic; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.