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Review Int J Mol Sci 2025

Exploring Oxygen Therapy as a Supporting Treatment for Asthma: Current Insights and Perspectives

Zwoliński M, Hovagimyan A, Ignatowicz J, Stelmasiak M, Lewicka A, Szopiński T, et al. — Int J Mol Sci, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed published experimental and clinical studies to summarize what is currently known about the potential role of HBOT as a supporting treatment for asthma.

What They Found

Preclinical and small clinical studies suggest HBOT may reduce airway inflammation, lower oxidative stress, modulate immune responses, and improve lung function in asthma. However, existing clinical evidence is limited and inconclusive, no large randomized controlled trials have confirmed whether HBOT works for asthma. Potential risks include barotrauma and oxygen toxicity.

What This Means for Canadian Patients

Over 3 million Canadians have asthma, and many still have poorly controlled symptoms despite standard medications. While HBOT for asthma is not currently a proven treatment, this review identifies it as a candidate for future study. Canadians with severe or steroid-resistant asthma should watch for clinical trials in this area.

Canadian Relevance

No direct Canadian connection identified. HBOT for asthma is not OHIP-covered in Ontario.

Study Limitations

This is a narrative review without a systematic methodology, and the clinical evidence it draws from consists mostly of small, poorly designed studies.

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Study Details

Study Type Review
Category Systematic Reviews
Source Pubmed
PubMed ID 41515904
Year Published 2025
Journal Int J Mol Sci
MeSH Terms Humans; Asthma; Hyperbaric Oxygenation; Animals; Oxidative Stress; Oxygen Inhalation Therapy; Oxygen

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.