What Researchers Did
Researchers reported a case of a 41-year-old woman who developed late-onset vascular complications following hyaluronic acid filler injection.
What They Found
The patient experienced delayed vascular complications 28 hours post-injection, which did not respond to low-dose hyaluronidase. Full recovery was achieved after escalation to high-dose hyaluronidase (6000 IU) combined with platelet-rich fibrin and hyperbaric oxygen therapy.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
As a single case report, the findings may not be generalizable to a broader patient population.