High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report | Canada Hyperbarics Skip to main content
Case Report J Oral Biol Craniofac Res 2024

High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report

Germani M, Alegria P, Giro G, Munoz-Lora V — J Oral Biol Craniofac Res, 2024

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a 34-year-old woman who developed nasal skin damage after a hyaluronic acid filler injection and was treated with hyaluronidase and hyperbaric oxygen therapy.

What They Found

The patient received 10,000 TRU of hyaluronidase in a high-dose pulsed manner, along with hyperbaric oxygen therapy. She showed gradual but significant improvement in her nasal skin necrosis over 60 days.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a single case report, these findings cannot be generalized to a larger patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Case Report
Category Aging & Longevity
Source Pubmed
PubMed ID 38699685
Year Published 2024
Journal J Oral Biol Craniofac Res

Cite This Study

Share

Find a Canadian Clinic

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology