Hyperbaric hyperoxia reversibly inhibits erythrocyte phospholipid fatty acid turnover. | Canada Hyperbarics Skip to main content
Clinical Study Journal of applied physiology (Bethesda, Md. : 1985) 1987

Hyperbaric hyperoxia reversibly inhibits erythrocyte phospholipid fatty acid turnover.

Dise CA, Clark JM, Lambersten CJ, Goodman DB — Journal of applied physiology (Bethesda, Md. : 1985), 1987

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers exposed 10 human subjects to hyperbaric hyperoxia and then studied the fatty acid turnover in their red blood cell membranes.

What They Found

They found that the incorporation of oleic acid into erythrocyte membrane phospholipids decreased by 30% after hyperbaric hyperoxia, with partial recovery observed 24 hours later. Additionally, the reduced glutathione content in intact erythrocytes increased by 15% after exposure and remained elevated.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study involved a small sample size of 10 subjects and focused on a specific cellular mechanism in vitro, which may not fully reflect complex in vivo responses.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Uncategorised
Source Pubmed
PubMed ID 3558213
Year Published 1987
Journal Journal of applied physiology (Bethesda, Md. : 1985)
MeSH Terms Adult; Erythrocytes; Fatty Acids; Humans; Hyperbaric Oxygenation; Male; Oxygen; Phospholipids

Cite This Study

Share

Find a Canadian Clinic Treating Uncategorised

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.