Hyperbaric or normobaric oxygen for acute carbon monoxide poisoning: a randomised controlled clinical trial. | Canada Hyperbarics Skip to main content
RCT The Medical journal of Australia 1999

Hyperbaric or normobaric oxygen for acute carbon monoxide poisoning: a randomised controlled clinical trial.

Scheinkestel CD, Bailey M, Myles PS, Jones K, Cooper DJ, Millar IL, et al. — The Medical journal of Australia, 1999

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomised controlled double-blind trial to compare hyperbaric oxygen with normobaric oxygen for neurological sequelae in patients with carbon monoxide poisoning.

What They Found

The study found that more patients in the hyperbaric oxygen group required additional treatments (28% vs 15%, P = 0.01 for all patients). Furthermore, hyperbaric oxygen patients showed a worse outcome in the learning test at treatment completion (P = 0.01 for all patients).

Canadian Relevance

This study was conducted in Australia and has no direct Canadian connection.

Study Limitations

A limitation of this study is its single-center design, which may affect the generalizability of the findings.

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Study Details

Study Type RCT
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 10092916
Year Published 1999
Journal The Medical journal of Australia
MeSH Terms Adult; Animals; Carbon Monoxide Poisoning; Double-Blind Method; Female; Humans; Hyperbaric Oxygenation; Male; Neuropsychological Tests; Oxygen Inhalation Therapy; Severity of Illness Index; Suicide, Attempted; Treatment Outcome; Victoria

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This study relates to Carbon Monoxide Poisoning. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology