Review Audiol Neurootol 2017

Hyperbaric Oxygen Therapy as Adjuvant Treatment for Idiopathic Sudden Sensorineural Hearing Loss after Failure of Systemic Steroids

Hosokawa S, Sugiyama K, Takahashi G, Hashimoto Y, Hosokawa K, Takebayashi S, et al. — Audiol Neurootol, 2017

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively reviewed clinical data from 167 patients with idiopathic sudden sensorineural hearing loss (ISSNHL) who did not respond to systemic steroids and subsequently received adjuvant hyperbaric oxygen therapy (HBOT).

What They Found

After HBOT, 16 patients (9.6%) experienced complete recovery, 16 (9.6%) had definite improvement, and 45 (26.9%) showed slight improvement. The overall hearing improvement rate in the HBOT group was 46.1% (77/167 cases), which was significantly higher than the 32.5% (52/160 cases) observed in a control group (p = 0.021).

What This Means for Canadian Patients

For Canadian patients experiencing idiopathic sudden sensorineural hearing loss that does not respond to initial steroid treatment, hyperbaric oxygen therapy may offer a potential alternative for improving hearing outcomes. This could provide an additional treatment option for individuals who have exhausted standard therapies.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Japan.

Study Limitations

A key limitation of this study is its retrospective design, which may introduce selection bias and limit the generalizability of the findings.

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Study Details

Study Type	Review
Category	Sudden Hearing Loss
Source	Pubmed
PubMed ID	28423374
Year Published	2017
Journal	Audiol Neurootol
MeSH Terms	Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Audiometry; Case-Control Studies; Child; Combined Modality Therapy; Comorbidity; Diabetes Mellitus; Female; Glucocorticoids; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Hydrocortisone; Hyperbaric Oxygenation; Hypertension; Male; Middle Aged; Prednisolone; Retrospective Studies; Smoking; Treatment Outcome; Vertigo; Young Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.