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RCT The American journal of sports medicine 1997

Hyperbaric oxygen therapy for acute ankle sprains.

Borromeo CN, Ryan JL, Marchetto PA, Peterson R, Bove AA — The American journal of sports medicine, 1997

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomised double-blind study with 32 subjects with acute ankle sprains to compare hyperbaric oxygen therapy with air treatment in a hyperbaric chamber.

What They Found

The hyperbaric oxygen group showed a significantly greater improvement in joint function, with the functional index improving from 0.40 to 6.3, compared to 0.8 to 5.3 in the air group. Subjective pain also decreased more substantially in the treatment group (from 3.3 to 0.8) than in the control group (from 2.6 to 0.3), though no differences were noted in foot and ankle volume, range of motion, or time to recovery (approximately 16 days for both).

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada nor involved Canadian researchers or participants.

Study Limitations

A limitation of this study is its small sample size of 32 participants, which may limit the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Uncategorised
Source Pubmed
PubMed ID 9302466
Year Published 1997
Journal The American journal of sports medicine
MeSH Terms Acute Disease; Adolescent; Adult; Analysis of Variance; Ankle Injuries; Double-Blind Method; Edema; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Pain; Proportional Hazards Models; Range of Motion, Articular

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology