Hyperbaric oxygen therapy for acute idiopathic sudden sensorineural hearing loss; a systematic review with meta-analysis | Canada Hyperbarics
Meta-Analysis Diving Hyperb Med 2025

Hyperbaric oxygen therapy for acute idiopathic sudden sensorineural hearing loss; a systematic review with meta-analysis

Newth A, Perleth M, Sherlock S, Romero L, Bennett M — Diving Hyperb Med, 2025

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted an updated systematic review and meta-analysis of seven randomized and pseudo-randomized studies to evaluate hyperbaric oxygen therapy (HBOT) for idiopathic sudden sensorineural hearing loss (ISSHL).

What They Found

Pooled analysis from five studies indicated that the chance of improvement following HBOT combined with steroids was greater than with steroids alone (RR 1.6, 95% CI 1.3 to 2...). However, data pooling was challenging due to variations in how pure tone average changes were reported across studies.

What This Means for Canadian Patients

For Canadian patients experiencing ISSHL, these findings suggest that adding hyperbaric oxygen therapy to standard steroid treatment could potentially improve hearing outcomes. This information may help inform treatment discussions and clinical guidelines for managing this condition.

Canadian Relevance

This study does not have a direct Canadian connection as none of the authors or institutions are identified as Canadian, nor does it specifically address Canadian healthcare contexts.

Study Limitations

A significant limitation was the difficulty in pooling data due to inconsistent reporting of pure tone average changes across the included studies.

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Study Details

Study Type Meta-Analysis
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 41364864
Year Published 2025
Journal Diving Hyperb Med
MeSH Terms Humans; Hyperbaric Oxygenation; Hearing Loss, Sudden; Hearing Loss, Sensorineural; Randomized Controlled Trials as Topic; Acute Disease

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.