Hyperbaric Oxygen Therapy for Ischemic Complications and Salvage Following Breast Reconstruction: A Systematic Review and Meta-Analysis | Canada Hyperbarics Skip to main content
Meta-Analysis Aesthetic Plast Surg 2026

Hyperbaric Oxygen Therapy for Ischemic Complications and Salvage Following Breast Reconstruction: A Systematic Review and Meta-Analysis

Machado G, Mokhtar J, Romão V, Ferreira M, Perin J, Kreutz-Rodrigues L, et al. — Aesthetic Plast Surg, 2026

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis to compare ischemic complications after breast reconstruction surgery in patients who received hyperbaric oxygen therapy (HBOT) versus those who did not.

What They Found

After analyzing seven studies, researchers found that HBOT did not significantly reduce complications like hematoma (p=0.25), skin necrosis (p=0.40), or the need for reoperation (p=0.08) following breast reconstruction. In groups where HBOT was used alone, pooled rates for seroma were 16.1%, surgical site infection (SSI) 18.8%, return to the operating room for debridement 12.6%, and explantation 21.6%.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study primarily included non-randomized studies, which limits the strength of the comparative evidence regarding HBOT's effectiveness.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Meta-Analysis
Category Uncategorised
Source Pubmed
PubMed ID 42310081
Year Published 2026
Journal Aesthetic Plast Surg

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: June 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology