Hyperbaric oxygen therapy for male infertility: a systematic review and meta-analysis on improving sperm quality and fertility outcomes. | Canada Hyperbarics Skip to main content
Meta-Analysis Medical gas research 2025

Hyperbaric oxygen therapy for male infertility: a systematic review and meta-analysis on improving sperm quality and fertility outcomes.

Liu B, Wang J, Liu L, Lv M, Zhou D, Li M — Medical gas research, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis of nine randomized controlled trials to evaluate the efficacy of hyperbaric oxygen therapy in treating male infertility.

What They Found

The meta-analysis of nine studies revealed significant improvements in sperm survival, density, morphology, normal sperm rates, and motility following hyperbaric oxygen therapy. It also demonstrated an increased clinical pregnancy rate when combined with conventional treatments.

What This Means for Canadian Patients

Canadian patients with male infertility might consider hyperbaric oxygen therapy as a potential adjunctive treatment to improve various sperm parameters. This therapy could offer a new option for enhancing fertility outcomes when used alongside existing conventional treatments.

Canadian Relevance

There is no specific Canadian connection identified for this study.

Study Limitations

The study's limitations include the small number of included trials and potential publication bias.

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Study Details

Study Type Meta-Analysis
Category Systematic Reviews
Source Pubmed
PubMed ID 40300888
Year Published 2025
Journal Medical gas research
MeSH Terms Hyperbaric Oxygenation; Humans; Male; Infertility, Male; Spermatozoa; Female; Pregnancy; Fertility; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.