Hyperbaric oxygen therapy improves clinical symptoms and functional capacity and modulates thalamic connectivity in ME/CFS: a prospective cohort study | Canada Hyperbarics Skip to main content
Cohort Study J Transl Med 2026

Hyperbaric oxygen therapy improves clinical symptoms and functional capacity and modulates thalamic connectivity in ME/CFS: a prospective cohort study

Kim L, Cammà G, Peters C, Mantwill M, Müller O, Leprêtre N, et al. — J Transl Med, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated whether 40 sessions of hyperbaric oxygen therapy (HBOT) could improve symptoms and brain function in 30 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

What They Found

Patients experienced significant improvements in physical functioning (SF-36 PF, g=0.71) and clinically meaningful reductions in pain (p=0.002) and fatigue (p<0.001). Exercise capacity (g=0.66), muscle strength (g=0.40), and information processing speed (g=0.52) also improved significantly after treatment. Functional MRI scans showed changes in thalamic connectivity in ME/CFS patients following HBOT.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a prospective cohort study with a relatively small sample size, which limits the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Cohort Study
Category Uncategorised
Source Pubmed
PubMed ID 42249466
Year Published 2026
Journal J Transl Med

Cite This Study

Share

Find a Canadian Clinic Treating Uncategorised

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: June 12, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology