Clinical Study Urologiia (Moscow, Russia : 1999) 2015

[HYPERBARIC OXYGEN THERAPY IN THE TREATMENT OF MALE INFERTILITY ASSOCIATED WITH INCREASED SPERM DNA FRAGMENTATION AND REACTIVE OXYGEN SPECIES IN SEMEN].

Metelev AY, Bogdanov AB, Ivkinl EV, Mitrokhin AA, Vodneva MM, Veliev EI — Urologiia (Moscow, Russia : 1999), 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effect of hyperbaric oxygenation (HBO) on sperm DNA fragmentation and reactive oxygen species (ROS) in 90 men with idiopathic infertility.

What They Found

In the treatment group (n=60) receiving HBO, sperm DNA fragmentation significantly decreased from 33.2% to 11.9%, and median ROS in sperm dropped from 0.89 to 0.39 mV/s (p < 0.05). Pregnancy after IVF occurred in 63.3% (38/60) of partners in the HBO group compared to 36.7% (11/30) in the control group (p < 0.05).

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Russia.

Study Limitations

The study's findings may be limited by its relatively small sample size and single-center design, potentially affecting generalizability.

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Study Details

Study Type	Clinical Study
Category	Uncategorised
Source	Pubmed
PubMed ID	26859943
Year Published	2015
Journal	Urologiia (Moscow, Russia : 1999)
MeSH Terms	Adult; DNA Fragmentation; Female; Fertilization in Vitro; Humans; Hyperbaric Oxygenation; Infertility, Male; Male; Oxidative Stress; Pregnancy; Reactive Oxygen Species

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.