Hyperbaric Oxygen Therapy Versus Intratympanic Steroid for Salvage Treatment of Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis. | Canada Hyperbarics Skip to main content
Meta-Analysis Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2021

Hyperbaric Oxygen Therapy Versus Intratympanic Steroid for Salvage Treatment of Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis.

Lei X, Feng Y, Xia L, Sun C — Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This meta-analysis compared the efficacy of hyperbaric oxygen therapy (HBOT) and intratympanic steroids (ITS) as salvage treatments for refractory sudden sensorineural hearing loss (SSNHL).

What They Found

Researchers found no significant difference in hearing improvement between HBOT and ITS (RR=1.09, 95% confidence interval: 0.83-1.42, p=0.55). Similarly, there was no significant difference in pure tone average changes between the two groups (MD=0.55, 95% confidence interval: -1.76-2.86, p=0.64).

What This Means for Canadian Patients

Canadian patients with refractory sudden sensorineural hearing loss may consider either hyperbaric oxygen therapy or intratympanic steroids as salvage treatment options. Both modalities offer some benefits, and the choice between them may depend on availability, cost, and patient preference.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study suggests a need for future large-sample randomized controlled trials to definitively establish the superiority of one treatment over the other.

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Study Details

Study Type Meta-Analysis
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 34172651
Year Published 2021
Journal Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
MeSH Terms Dexamethasone; Glucocorticoids; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Injection, Intratympanic; Salvage Therapy; Steroids; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.