Hyperbaric treatment of platelets is comparable to cold storage alone over 14 days | Canada Hyperbarics Skip to main content
Study Transfusion 2023

Hyperbaric treatment of platelets is comparable to cold storage alone over 14 days

Reddoch-Cardenas K, Pidcoke H, Ramasubramanian A, Meledeo M, Cap A — Transfusion, 2023

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared storing blood platelets in a hyperbaric chamber with xenon gas at 4 bars for 14 days to standard cold storage and room temperature storage to see if it extended their shelf life.

What They Found

Platelet counts in the hyperbaric xenon group were higher than in cold-stored samples but lower than room temperature samples. While glycoprotein expression was better preserved with hyperbaric xenon compared to cold storage, no differences in platelet activation were observed. Overall, tests for clot strength and platelet aggregation showed comparable results across all storage groups, indicating no significant improvement in platelet function with hyperbaric xenon over cold storage alone.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The use of a hyperbaric chamber and the slow off-gassing of xenon-stored units add practical complications to platelet storage and delivery logistics.

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Study Details

Study Type Study
Category Uncategorised
Source Pubmed
PubMed ID 37072924
Year Published 2023
Journal Transfusion
MeSH Terms Humans; Blood Preservation; Blood Platelets; Cryopreservation; Cold Temperature; Platelet Aggregation

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.