Impact of hyperbaric oxygen therapy on the clinical course of acute pancreatitis and systemic inflammation response syndrome

What Researchers Did

This prospective controlled study investigated the feasibility and impact of hyperbaric oxygen therapy (HBO) as an adjunct treatment for 44 patients with acute pancreatitis and systemic inflammatory response syndrome.

What They Found

Researchers observed more stable homeostasis, a decreased mortality rate, and fewer operations in the HBO group (n=22) compared to the control group (n=22). HBO therapy also potentially contributed to a decrease in intraabdominal pressure within the first six days and modulated the inflammatory response by altering cytokine levels.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.

Study Limitations

A limitation of this study is its relatively small sample size of 44 patients, which may limit the generalizability of the findings.