What Researchers Did
This systematic review assessed the effects of various medical and surgical treatments for necrotizing soft tissue infections (NSTIs) in adults within hospital settings.
What They Found
Necrotizing soft tissue infections (NSTIs) are associated with high mortality, estimated at around 23%, and result in disability, sequelae, or limb loss for 15% of patients. The review focused on standard treatments such as antimicrobial therapy, surgical debridement, and intensive care support, but explicitly excluded randomised controlled trials (RCTs) investigating hyperbaric oxygen therapy for NSTI.
Canadian Relevance
No direct Canadian connection identified, as the study was not conducted by Canadian authors or in Canada. Furthermore, the review explicitly excluded hyperbaric oxygen therapy, which is relevant to Canada Hyperbarics' focus.
Study Limitations
A significant limitation is the explicit exclusion of randomised controlled trials investigating hyperbaric oxygen therapy for necrotizing soft tissue infections.