Nonsurgical Approach to Treat Post-Rhinoplasty Vascular Complication With Hyaluronic Acid Injection | Canada Hyperbarics Skip to main content
Study J Cosmet Dermatol 2025

Nonsurgical Approach to Treat Post-Rhinoplasty Vascular Complication With Hyaluronic Acid Injection

Qiang S, Fan X, Yin Y, Xue P, Dou W, Li T, et al. — J Cosmet Dermatol, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Chinese cosmetic surgeons reviewed outcomes for 41 women who developed tissue-threatening vascular complications after nose filler injections, all treated with a protocol that included HBOT, enzyme injections, skin growth factor gel, steroids, and a blood vessel dilator.

What They Found

All 41 patients achieved complete wound healing. Patients who sought treatment within 48 hours had significantly fewer lasting skin color changes (p < 0.05). Residual complications included scar formation (21.9%), visible small blood vessels (39.0%), and pigmentation changes (53.7%). HBOT was one component of the multi-treatment protocol used for all patients.

What This Means for Canadian Patients

Filler-related vascular injuries are a serious risk of cosmetic procedures and can cause permanent facial scarring. This study reinforces that HBOT combined with other early interventions can prevent tissue death and that time to treatment matters, within 48 hours is the key window.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study had no control group, used HBOT as part of a multi-drug protocol, and all patients were from a single cosmetic centre, making it impossible to determine how much HBOT alone contributed to the outcomes.

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Study Details

Study Type Study
Category Aging & Longevity
Source Pubmed
PubMed ID 40586313
Year Published 2025
Journal J Cosmet Dermatol
MeSH Terms Humans; Female; Hyaluronic Acid; Adult; Retrospective Studies; Dermal Fillers; Hyperbaric Oxygenation; Hyaluronoglucosaminidase; Rhinoplasty; Middle Aged; Nitroglycerin; Telangiectasis; Necrosis; Skin; Treatment Outcome; Ischemia; Vasodilator Agents; Young Adult; Adrenal Cortex Hormones; Combined Modality Therapy

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.