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Prospective Study Radiother Oncol 2003

Prospective trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas

Ogawa K, Yoshii Y, Inoue O, Toita T, Saito A, Kakinohana Y, et al. — Radiother Oncol, 2003

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a prospective trial with 21 patients diagnosed with high-grade brain tumours, administering radiation therapy immediately after hyperbaric oxygen treatments, alongside chemotherapy.

What They Found

The study concluded that giving radiation therapy right after hyperbaric oxygen therapy, combined with chemotherapy, was a feasible approach for treating high-grade brain tumours. This abstract did not report specific outcomes such as survival rates or tumour response.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A limitation of this study is its small sample size of 21 patients and that it focused only on the feasibility of the treatment, not its effectiveness or long-term patient outcomes.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Prospective Study
Category Uncategorised
Source Pubmed
PubMed ID 12758241
Year Published 2003
Journal Radiother Oncol
MeSH Terms Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Hyperbaric Oxygenation; Japan; Male; Middle Aged; Nimustine; Procarbazine; Prospective Studies; Supratentorial Neoplasms; Survival Rate; Vincristine

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology