Randomized prospective trial of hyperbaric oxygen therapy and intratympanic steroid injection as salvage treatment of sudden sensorineural hearing loss | Canada Hyperbarics Skip to main content
RCT Otol Neurotol 2013

Randomized prospective trial of hyperbaric oxygen therapy and intratympanic steroid injection as salvage treatment of sudden sensorineural hearing loss

Cvorovic L, Jovanovic M, Milutinovic Z, Arsovic N, Djeric D — Otol Neurotol, 2013

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a prospective randomized trial comparing hyperbaric oxygen therapy and intratympanic steroid injection as salvage treatments for idiopathic sudden sensorineural hearing loss after initial therapy failed.

What They Found

Among 50 patients with idiopathic sudden sensorineural hearing loss who failed primary treatment, both hyperbaric oxygen (HBO) and intratympanic (IT) steroid treatments resulted in significant hearing improvements. Specifically, HBO led to significant hearing threshold differences at all tested frequencies, while IT steroids showed significant differences at most frequencies except 2 kHz. Patients with a pure tone average less than 81 dB and younger than 60 years old responded better to HBO therapy.

What This Means for Canadian Patients

Canadian patients experiencing sudden sensorineural hearing loss that does not respond to initial treatment may have two viable salvage therapy options: hyperbaric oxygen therapy or intratympanic steroid injections. These findings suggest that if primary treatment fails, these secondary interventions could still offer a chance for hearing improvement.

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

A limitation of this study is that the patient groups were not matched or similar, and further research is needed to determine which treatment is superior.

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Study Details

Study Type RCT
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 23820795
Year Published 2013
Journal Otol Neurotol
MeSH Terms Adult; Anti-Inflammatory Agents; Audiometry, Pure-Tone; Auditory Threshold; Dexamethasone; Female; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Injections; Male; Middle Aged; Salvage Therapy; Treatment Failure; Tympanic Membrane

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.