Recompression and Adjunctive Therapies in DCI Management in Divers: A Review of RCTs | Canada Hyperbarics
RCT Undersea Hyperb Med 2025

Recompression and Adjunctive Therapies in DCI Management in Divers: A Review of RCTs

Fairhead T — Undersea Hyperb Med, 2025

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

A researcher systematically reviewed all randomized controlled trials on recompression treatment and add-on therapies for divers with decompression illness (DCI).

What They Found

Only two RCTs were found in the entire medical literature. One trial (180 patients) showed that tenoxicam (an anti-inflammatory drug) reduced the median number of recompression sessions needed from 3 to 2. The second trial (41 patients) showed a shorter initial recompression table reduced repeat sessions (median 1 versus 2) for mild DCI cases. Both trials had significant methodological limitations.

What This Means for Canadian Patients

For Canadian divers who experience decompression illness, this review reveals that current treatment protocols, including HBOT recompression, are based on very limited controlled trial evidence. While HBOT remains the standard of care for DCI, Canadians should be aware that the precise best protocol is still being refined, and that non-steroidal anti-inflammatory drugs may reduce the number of chamber sessions needed.

Canadian Relevance

Decompression sickness is an OHIP-covered indication for HBOT in Ontario.

Study Limitations

Only two eligible RCTs exist worldwide, both small and with methodological weaknesses, making it impossible to draw firm conclusions about optimal HBOT protocols for DCI.

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Study Details

Study Type RCT
Category Decompression Sickness
Source Pubmed
PubMed ID 41429038
Year Published 2025
Journal Undersea Hyperb Med
MeSH Terms Humans; Decompression Sickness; Randomized Controlled Trials as Topic; Diving; Hyperbaric Oxygenation; Piroxicam

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.