Results of the First Clinical Study in Humans That Combines Hyperbaric Oxygen Pretreatment with Autologous Peripheral Blood Stem Cell Transplantation. | Canada Hyperbarics Skip to main content
Clinical Study Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2019

Results of the First Clinical Study in Humans That Combines Hyperbaric Oxygen Pretreatment with Autologous Peripheral Blood Stem Cell Transplantation.

Abdelhakim H, Shune L, Bhatti S, Cantilena AR, Baran A, Lin TL, et al. — Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted the first clinical study to evaluate hyperbaric oxygen pretreatment combined with autologous peripheral blood stem cell transplantation in humans.

What They Found

The provided abstract outlines the rationale for this first-in-human clinical study, citing preclinical evidence that hyperbaric oxygen (HBO) pretreatment may improve outcomes in hematopoietic cell transplantation. However, the specific findings and numerical results of this clinical trial are not included in the provided abstract.

What This Means for Canadian Patients

If future research confirms the benefits of hyperbaric oxygen pretreatment, it could offer a novel strategy to reduce complications like mucosal inflammation and neutropenic fever for Canadian patients undergoing autologous hematopoietic cell transplantation. This could potentially improve recovery and quality of life for these patients.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation is that the provided abstract is incomplete and does not detail the specific findings or numerical results of this clinical study.

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Study Details

Study Type Clinical Study
Category Uncategorised
Source Pubmed
PubMed ID 31170519
Year Published 2019
Journal Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
MeSH Terms Aged; Allografts; Disease-Free Survival; Female; Hematologic Neoplasms; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Pilot Projects; Survival Rate

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.