Role of Hyperbaric Oxygenation Plus Hypofractionated Stereotactic Radiotherapy in Recurrent High-Grade Glioma | Canada Hyperbarics Skip to main content
Study Front Oncol 2021

Role of Hyperbaric Oxygenation Plus Hypofractionated Stereotactic Radiotherapy in Recurrent High-Grade Glioma

Arpa D, Parisi E, Ghigi G, Cortesi A, Longobardi P, Cenni P, et al. — Front Oncol, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated an innovative approach combining hyperbaric oxygen therapy with hypofractionated stereotactic radiotherapy to treat nine adult patients with recurrent high-grade glioma.

What They Found

After a median follow-up of 11.6 months, 55.5% of patients showed disease control three months after receiving radiation therapy within 60 minutes of hyperbaric oxygen. The median time patients lived without their disease getting worse was 5.2 months, and their median overall survival was 10.7 months. Notably, 88.88% of patients experienced no significant neurological side effects, with one patient developing severe radionecrosis.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This study was an interim analysis conducted on a small preliminary group of only nine patients, limiting the generalizability of the findings.

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Study Details

Study Type Study
Category Uncategorised
Source Pubmed
PubMed ID 33859944
Year Published 2021
Journal Front Oncol

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.