Hyperbaric oxygen therapy for patients with sudden... (2022 study) Skip to main content
Meta-Analysis JAMA Otolaryngol 2022 Canadian

Hyperbaric oxygen therapy for patients with sudden sensorineural hearing loss: a systematic review and meta-analysis

Joshua TG, Ayub A, Bhatt J, et al., JAMA Otolaryngol, 2022

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers pooled results from randomized controlled trials to see whether hyperbaric oxygen therapy (HBOT) improves hearing recovery in adults with sudden sensorineural hearing loss.

What They Found

This systematic review and meta-analysis of randomized controlled trials found that HBOT was associated with better hearing recovery than control treatments, with a mean difference in hearing gain of 10.3 decibels (95% CI, 6.5-14.1) favoring HBOT. Patients who received HBOT also had higher odds of hearing recovery, with an odds ratio of 4.3 (95% CI, 1.6-11.7) compared to control therapies. These results were based on data extracted independently by two researchers and analyzed using a fixed-effects model.

What This Means for Canadian Patients

For Canadian patients with sudden sensorineural hearing loss, this analysis suggests HBOT, used alongside standard treatments like steroids, was linked to greater hearing improvement in the trials reviewed. Patients experiencing sudden hearing loss should still seek prompt medical evaluation, since the abstract describes HBOT as part of a treatment approach alongside steroids rather than a standalone replacement.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The analysis was restricted to English-language randomized controlled trials published between January 2000 and April 2020 and used a fixed-effects model, which may not fully capture variation across the included trials.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Meta-Analysis
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 34709348
Year Published 2022
Journal JAMA Otolaryngol

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This study relates to Sudden Sensorineural Hearing Loss. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology