The effect of acute hyperoxia in vivo on NF kappa B expression in human PBMC | Canada Hyperbarics Skip to main content
Study Cell Biochem Funct 2011

The effect of acute hyperoxia in vivo on NF kappa B expression in human PBMC

Madden L, Vince R, Laden G — Cell Biochem Funct, 2011

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated NFκB expression in peripheral blood mononuclear cells (PBMC) of ten healthy male volunteers before and after a single hyperbaric oxygen (HBO) treatment.

What They Found

Mean NFκB expression was 0.27 absorbance units pre-HBO, increasing to 0.29 immediately post-HBO. A significant increase in NFκB expression (mean 0.38, p=0.027) was observed in PBMC four hours after HBO treatment compared to pre-treatment levels.

Canadian Relevance

This study has no specific Canadian connection.

Study Limitations

A limitation of this study is its small sample size of ten healthy male volunteers and the focus on a single acute HBO treatment.

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Study Details

Study Type Study
Category Uncategorised
Source Pubmed
PubMed ID 21264893
Year Published 2011
Journal Cell Biochem Funct
MeSH Terms Cell Nucleus; Humans; Hyperbaric Oxygenation; Hyperoxia; Leukocytes, Mononuclear; Male; NF-kappa B; Reactive Oxygen Species

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.