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Prospective Study Photodiagnosis and photodynamic therapy 2022

The effect of hyperbaric oxygen therapy on retina, choroidal thickness, and choroidal vascularity index.

Tukenmez Dikmen N, Akyol UC, Comerter D, Sadik MT, Demir N, Sumen SG, et al. — Photodiagnosis and photodynamic therapy, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a prospective study on 35 healthy individuals undergoing hyperbaric oxygen therapy (HBOT) to assess its acute and cumulative effects on retinal and choroidal structures using SD-OCT.

What They Found

They found a statistically significant decrease in central macular thickness (CMT) from 259.36 µm before HBOT to 254.58 µm after 20 sessions (p=0.001).

However, no significant changes were observed in retinal nerve fiber layer, choroidal thickness, choroidal area, luminal area, stromal area, or choroidal vascularity index (p>0.05).

What This Means for Canadian Patients

Canadian patients undergoing hyperbaric oxygen therapy for non-ophthalmologic conditions may experience a small, statistically significant decrease in central macular thickness.

However, other important eye structures like the retinal nerve fiber layer and choroidal vascularity appear to remain unaffected by HBOT.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor does it involve Canadian researchers or specific Canadian health data.

Study Limitations

The study's findings are limited to healthy eyes undergoing HBOT for non-ophthalmologic reasons, and the long-term effects beyond 20 sessions were not evaluated.

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Study Details

Study Type Prospective Study
Category Aging & Longevity
Source Pubmed
PubMed ID 35390520
Year Published 2022
Journal Photodiagnosis and photodynamic therapy
MeSH Terms Adult; Choroid; Humans; Hyperbaric Oxygenation; Middle Aged; Photochemotherapy; Prospective Studies; Retina; Retrospective Studies; Tomography, Optical Coherence; Young Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.