The Effects of Hyperbaric Oxygenation on Oxidative Stress, Inflammation and Angiogenesis. | Canada Hyperbarics Skip to main content
Review Biomolecules 2021

The Effects of Hyperbaric Oxygenation on Oxidative Stress, Inflammation and Angiogenesis.

De Wolde SD, Hulskes RH, Weenink RP, Hollmann MW, Van Hulst RA — Biomolecules, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review to investigate the effects of hyperbaric oxygen therapy (HBOT) on oxidative stress, inflammation, and angiogenesis, particularly as a preconditioning treatment for surgery.

What They Found

The review found that HBOT-induced oxidative stress reduced concentrations of pro-inflammatory acute phase proteins, interleukins, and cytokines. It also increased growth factors and other pro-angiogenesis cytokines, though this surge was often noted only after the first HBOT session or for a short duration.

What This Means for Canadian Patients

If further research confirms these findings, Canadian patients undergoing surgery might benefit from hyperbaric oxygen therapy as a preconditioning treatment. This could potentially lead to reduced post-surgical complications and shorter hospital stays.

Canadian Relevance

This review article has no direct Canadian connection.

Study Limitations

The review highlights the need for further research to fully determine the clinical implications of HBOT's effects on inflammation and angiogenesis.

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Study Details

Study Type Review
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 34439876
Year Published 2021
Journal Biomolecules
MeSH Terms Biomarkers; Humans; Hyperbaric Oxygenation; Inflammation; Neovascularization, Pathologic; Oxidative Stress

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.