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Review Medicinal chemistry (Shariqah (United Arab Emirates)) 2019

The Multiple Applications and Possible Mechanisms of the Hyperbaric Oxygenation Therapy.

Chen W, Liang X, Nong Z, Li Y, Pan X, Chen C, et al. — Medicinal chemistry (Shariqah (United Arab Emirates)), 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed the current applications and possible mechanisms of Hyperbaric Oxygenation Therapy (HBOT).

What They Found

They found that Hyperbaric Oxygenation Therapy (HBOT) shows therapeutic efficacy for conditions like angiogenesis, tissue ischemia, nerve system diseases, diabetic complications, malignancies, carbon monoxide poisoning, and chronic radiation-induced injury. However, HBOT also carries risks including oxidative stress injury, DNA damage, cellular metabolic changes, coagulation activation, endothelial dysfunction, acute neurotoxicity, and pulmonary toxicity.

What This Means for Canadian Patients

Canadian patients considering Hyperbaric Oxygenation Therapy (HBOT) should discuss its potential benefits for conditions like tissue ischemia or diabetic complications with their healthcare provider. It is crucial to also understand the associated risks, such as oxidative stress or neurotoxicity, to make an informed decision about this adjunctive treatment.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The review acknowledges that the overall applicability and validity of Hyperbaric Oxygenation Therapy for clinical treatment remain controversial.

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Study Details

Study Type Review
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 30569869
Year Published 2019
Journal Medicinal chemistry (Shariqah (United Arab Emirates))
MeSH Terms Animals; Cardiovascular Diseases; Humans; Hyperbaric Oxygenation; Hypoxia; Ischemia; Neovascularization, Physiologic; Nervous System Diseases

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.