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Systematic Review Int Urogynecol J 2016

Treatment of bladder pain syndrome and interstitial cystitis: a systematic review

Pazin C, de Souza Mitidieri A, Silva A, Gurian M, Poli-Neto O, Rosa-E-Silva J — Int Urogynecol J, 2016

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers conducted a systematic review to analyze various treatments for bladder pain syndrome/interstitial cystitis (BPS/IC) and their effectiveness.

What They Found

Out of 356 articles reviewed, 13 were included in the analysis. The interventions studied included instillation of hyaluronic acid, botulinum toxin A, intravesical lidocaine, and hyperbaric chamber treatments, among others. However, the review found no single treatment with at least two randomised controlled trials to establish a best approach for BPS/IC.

What This Means for Canadian Patients

For Canadian patients with bladder pain syndrome/interstitial cystitis, this review highlights the current lack of a universally accepted or standardised treatment. Patients may encounter a variety of approaches, reflecting the ongoing challenge in finding effective and consistent therapies for this condition.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The review was limited by the diversity of interventions and the lack of high-quality, standardised studies, preventing the definition of a best treatment approach for BPS/IC.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Systematic Review
Category Systematic Reviews
Source Pubmed
PubMed ID 26272202
Year Published 2016
Journal Int Urogynecol J
MeSH Terms Acetylcholine Release Inhibitors; Adjuvants, Immunologic; Administration, Intravesical; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Botulinum Toxins, Type A; Cystitis, Interstitial; Drug Therapy, Combination; Female; Humans; Hyaluronic Acid; Hyperbaric Oxygenation; Lidocaine; Pentosan Sulfuric Polyester; Physical Therapy Modalities; Sodium Chloride

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology