What Researchers Did
Researchers managed two patients with oral bisphosphonate-associated osteonecrosis of the jaw using platelet-rich plasma, with one case also receiving hyperbaric oxygen.
What They Found
They achieved complete remission in both 2 cases, defined as resolution of pain and complete closure of exposed bone in the jaws. This outcome was observed in 100% of the treated patients.
What This Means for Canadian Patients
Canadian patients suffering from oral bisphosphonate-associated osteonecrosis of the jaw might benefit from treatment protocols incorporating platelet-rich plasma. This approach could offer hope for complete remission where traditional treatments have been refractory.
Canadian Relevance
This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.
Study Limitations
A significant limitation of this study is its very small sample size, reporting on only two cases.