Veno-venous extracorporeal blood phototherapy increases the rate of carbon monoxide (CO) elimination in CO-poisoned pigs. | Canada Hyperbarics Skip to main content
Clinical Study Lasers in surgery and medicine 2022

Veno-venous extracorporeal blood phototherapy increases the rate of carbon monoxide (CO) elimination in CO-poisoned pigs.

Fischbach A, Wiegand SB, Zazzeron L, Traeger L, di Fenza R, Bagchi A, et al. — Lasers in surgery and medicine, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers developed and tested a larger photo-ECMO device and system for removing carbon monoxide (CO) from blood in a porcine model of CO poisoning.

What They Found

The photo-ECMO device effectively oxygenated blood after a single pass. Illumination with red light combined with 100% oxygen was twice as efficient in removing carbon monoxide from blood compared to 100% oxygen ventilation alone.

What This Means for Canadian Patients

This research suggests a potential novel treatment approach for carbon monoxide poisoning, especially in cases where hyperbaric oxygen therapy is unavailable or delayed. If proven effective in humans, this technology could offer a more accessible and efficient way to remove CO from the blood, potentially improving patient outcomes.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor does it involve Canadian researchers or patient populations.

Study Limitations

A key limitation is that the study was conducted in a porcine model and in vitro, meaning further human trials are needed to confirm efficacy and safety.

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Study Details

Study Type Clinical Study
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 34350599
Year Published 2022
Journal Lasers in surgery and medicine
MeSH Terms Animals; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Humans; Phototherapy; Poisons; Rats; Swine

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.