A 26-year-old woman of interval form of acute carbon monoxide intoxication with cerebrospinal fluid abnormalities. | Canada Hyperbarics Skip to main content
Clinical Study No to shinkei = Brain and nerve 2005

A 26-year-old woman of interval form of acute carbon monoxide intoxication with cerebrospinal fluid abnormalities.

Kono Y, Nakamori T, Imafuku I, Washizaki K, Kunimoto M — No to shinkei = Brain and nerve, 2005

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a 26-year-old woman who developed delayed neurological symptoms after acute carbon monoxide intoxication and was successfully treated with hyperbaric oxygen therapy and cytochrome C.

What They Found

The patient initially improved after 23 hyperbaric oxygen treatments but was readmitted 22 days later with dementia and urinary incontinence. She fully recovered after 38 additional hyperbaric oxygen treatments with cytochrome C, with MRI and cerebrospinal fluid abnormalities normalizing later. This was noted as the first report of abnormal cerebrospinal fluid findings in interval form carbon monoxide intoxication.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a single case report, the findings cannot be generalized to a broader patient population.

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Study Details

Study Type Clinical Study
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 16095223
Year Published 2005
Journal No to shinkei = Brain and nerve
MeSH Terms Adult; Brain; Carbon Monoxide Poisoning; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Cytochromes c; Dementia; Diffusion Magnetic Resonance Imaging; Female; Fetal Death; Humans; Hyperbaric Oxygenation; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology