A modified protocol to treat early osteoradionecrosis of the mandible. | Canada Hyperbarics Skip to main content
Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 1995

A modified protocol to treat early osteoradionecrosis of the mandible.

Aitasalo K, Grénman R, Virolainen E, Niinikoski J, Klossner J — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 1995

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers treated 17 patients with osteoradionecrosis of the mandible or maxilla using a modified protocol involving surgery and hyperbaric oxygen therapy.

What They Found

Out of 17 patients treated for osteoradionecrosis with surgery and hyperbaric oxygen, 16 remained symptom free after the initial treatment period. One patient's early treatment failed but was successfully resolved with a free microvascular flap.

What This Means for Canadian Patients

Canadian patients suffering from osteoradionecrosis of the jaw might benefit from this combined surgical and hyperbaric oxygen approach. This treatment could offer a promising option for achieving long-term symptom relief.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The study was limited by its small sample size and the absence of a control group for comparison.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 7633278
Year Published 1995
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Adult; Aged; Combined Modality Therapy; Female; Humans; Hyperbaric Oxygenation; Male; Mandibular Diseases; Middle Aged; Osteoradionecrosis

Cite This Study

Share

This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

Find a Canadian Clinic Treating Radiation Injury

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology